SCHEMBL992105

SCHEMBL992105

NOCc1ccc(Cl)c(Cl)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 13/20 1.00
AGXT P21549 4/20 0.58
CYP3A4 P08684 2/20 0.55
PNMT P11086 2/20 0.54
TAAR1 Q96RJ0 1/20 0.54
NPC1 O15118 2/20 0.49
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30080027 1.00 IDO1 (1.00) IDO1AGXTCYP3A4PNMTTAAR1
Hydrochloric Acid SCHEMBL1715800 0.98 IDO1 (1.00) IDO1AGXTCYP3A4PNMTTAAR1
SCHEMBL30873130 0.81 IDO1 (0.68) IDO1PNMTTAAR1NPC1MAPT
SCHEMBL865549 0.81 IDO1 (0.68) IDO1PNMTTAAR1NPC1MAPT
SCHEMBL1520817 0.81 IDO1 (0.68) IDO1AGXTCYP3A4
SCHEMBL24074516 0.77 IDO1 (0.63) IDO1PNMTTAAR1NPC1MAPT
SCHEMBL791989 0.77 IDO1 (0.63) IDO1PNMTTAAR1NPC1MAPT
SCHEMBL2093527 0.77 IDO1 (0.63) IDO1PNMTTAAR1NPC1MAPT
SCHEMBL1859313 0.77 IDO1 (1.00) IDO1AGXTCYP3A4
SCHEMBL11023152 0.76 IDO1 (0.61) IDO1PNMTTAAR1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11661436-B2 Method for preparing 3′-o-amino-2′-deoxyribonucleoside-5′-triphosphates DNA SCRIPT SAS (FR) 2023-05-30 US claimed
CN-115362161-A Process for preparing 3' -O-amino-2 ' -deoxyribonucleoside-5 ' -triphosphates DNA斯克瑞普特公司 2022-11-18 CN claimed
US-20210300961-A1 METHOD FOR PREPARING 3'-O-AMINO-2'-DEOXYRIBONUCLEOSIDE-5'-TRIPHOSPHATES DNA SCRIPT SAS (FR) 2021-09-30 US claimed
US-11661436-B2 Method for preparing 3′-o-amino-2′-deoxyribonucleoside-5′-triphosphates DNA SCRIPT SAS (FR) 2023-05-30 US disclosed
CN-115362161-A Process for preparing 3' -O-amino-2 ' -deoxyribonucleoside-5 ' -triphosphates DNA斯克瑞普特公司 2022-11-18 CN disclosed
US-20210300961-A1 METHOD FOR PREPARING 3'-O-AMINO-2'-DEOXYRIBONUCLEOSIDE-5'-TRIPHOSPHATES DNA SCRIPT SAS (FR) 2021-09-30 US disclosed
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
EP-2456782-B1 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-BENZYLIDENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES BAYER IP GMBH (DE) 2015-08-19 EP disclosed
EP-2456783-B1 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-ETHINYLPHENYL DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES BAYER IP GMBH (DE) 2015-08-19 EP disclosed
US-9102701-B2 17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-ethynylphenyl derivatives, methods for the production thereof and use thereof for treating diseases BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-08-11 US disclosed
US-20130289083-A1 IDO Inhibitors NEWLINK GENETICS CORPORATION 2013-10-31 US disclosed
US-20060128642-A1 9-Ketospinosyn derivatives BAYER CROPSCIENCE AG (DE) 2006-06-15 US disclosed
EP-1590358-A1 9-KETOSPINOSYN DERIVATIVES Bayer CropScience Aktiengesellschaft (DE) 2005-11-02 EP disclosed
WO-2004065402-A1 9-KETOSPINOSYN DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-08-05 WO disclosed
EP-0387499-B1 Substituted oxine ethers and their use as pesticides BAYER AG (DE) 1993-12-22 EP disclosed
EP-0387499-A2 Substituted oxine ethers and their use as pesticides BAYER AG (DE) 1990-09-19 EP disclosed
US-4517183-A COMBATING DISEASES WITH WEAKNESS OF IMMUNE SYSTEMS BOEHRINGER MANNHEIM GMBH (DE) 1985-05-14 US disclosed
EP-0014976-B1 N-SUBSTITUTED 2-CYANAZIRIDINES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM, CORRESPONDINGLY SUBSTITUTED AZIRIDINE-2-CARBONAMIDES AND THEIR PREPARATION Roche Diagnostics GmbH (DE) 1982-04-07 EP disclosed
EP-0015456-B1 OMEGA-HALOGENO-ACETOPHENONE OXIME ETHERS, PREPARATION THEREOF AND THEIR USE AS INTERMEDIATES IN THE PREPARATION OF OMEGA-AZOLYL-ACETOPHENONE OXIME ETHERS BAYER AG (DE) 1981-12-02 EP disclosed
US-4293715-A FUNGICIDES, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210300961-A1 METHOD FOR PREPARING 3'-O-AMINO-2'-DEOXYRIBONUCLEOSIDE-5'-TRIPHOSPHATES DUT, RNMT, NUDT1 IDO1 997/4885AGXT 971/4885CYP3A4 825/4885
US-20060128642-A1 9-Ketospinosyn derivatives SNX9, NANS, BROX IDO1 1786/4885AGXT 103/4885CYP3A4 2733/4885
US-11661436-B2 Method for preparing 3′-o-amino-2′-deoxyribonucleoside-5′-triphosphates DUT, RNMT, NUDT1 IDO1 984/4885AGXT 924/4885CYP3A4 879/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 IDO1 2645/4885AGXT 485/4885CYP3A4 4336/4885
US-20130289083-A1 IDO Inhibitors IDO1, IDO2, INMT IDO1 1/4885AGXT 285/4885CYP3A4 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.