Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813445 | 0.89 | CHRM1 (0.52) | HMGCRCHRM1TBXA2RADRA1AGPR84 | |
| SCHEMBL13800594 | 0.81 | HMGCR (0.52) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL11430722 | 0.74 | GPR84 (0.38) | GPR84FFAR4FFAR1CA2MAPK1 | |
| Citric Acid SCHEMBL424042 | 0.74 | ALDH1A1 (0.52) | GPR84FFAR4FFAR1HSPD1BLM | |
| SCHEMBL22028547 | 0.73 | GPR84 (0.47) | GPR84FFAR4FFAR1CA2MAPK1 | |
| SCHEMBL13701361 | 0.72 | HMGCR (0.61) | HMGCRCHRM1TBXA2RADRA1AGPR84 | |
| SCHEMBL380849 | 0.72 | HMGCR (0.61) | HMGCRCHRM1TBXA2RADRA1AGPR84 | |
| SCHEMBL12595644 | 0.72 | GPR84 (0.39) | GPR84FFAR4FFAR1CA2MAPK1 | |
| SCHEMBL10898444 | 0.72 | GPR84 (0.46) | GPR84FFAR4FFAR1BLM | |
| Citric Acid SCHEMBL426273 | 0.71 | ALDH1A1 (0.48) | GPR84FFAR4FFAR1HSPD1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9585964-B2 | Liver targeted conjugates | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-07 | — | — | US | disclosed |