Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 10/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872528 | 1.00 | MAOB (0.56) | MAOBTRPA1ALDH1A1TSHRTOP1 | |
| SCHEMBL433496 | 0.88 | MAOB (0.71) | MAOBALDH1A1TOP1TDP1GPR52 | |
| SCHEMBL28679572 | 0.88 | MAOB (0.71) | MAOBALDH1A1TOP1TDP1GPR52 | |
| SCHEMBL18595441 | 0.88 | MAOB (0.71) | MAOBALDH1A1TOP1TDP1GPR52 | |
| SCHEMBL9715286 | 0.79 | GPR52 (0.57) | MAOBALDH1A1TDP1GPR52 | |
| SCHEMBL7762164 | 0.79 | GPR52 (0.57) | MAOBALDH1A1TDP1GPR52 | |
| SCHEMBL7762166 | 0.79 | GPR52 (0.57) | MAOBALDH1A1TDP1GPR52 | |
| SCHEMBL11387574 | 0.78 | TDP1 (0.58) | MAOBTRPA1ALDH1A1TSHRTDP1 | |
| SCHEMBL6761553 | 0.78 | TDP1 (0.52) | MAOBTRPA1ALDH1A1TSHRTDP1 | |
| SCHEMBL11387571 | 0.78 | TDP1 (0.58) | MAOBTRPA1ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015473-A1 | LEUCOTRIENE ANTAGONISTS, A PREPARATION METHOD THEREFOR AND THERAPEUTIC USES THEREOF | LABORATOIRES FOURNIER S.C.A. (FR) | 1991-10-17 | — | — | WO | disclosed |