SCHEMBL18595449

SCHEMBL18595449

CC(CCC=O)OCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.42
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPT P10636 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
RCE1 Q9Y256 1/20 0.38
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
AOX1 Q06278 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8917997 0.90 SLC1A3 (0.41) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL16177521 0.83 SLC1A3 (0.41) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL31644832 0.83 MAPT (0.39) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL8968891 0.83 MAPT (0.39) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL11577777 0.82 SLC1A3 (0.45) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL27710467 0.80 KMT2A (0.41) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL28285993 0.79 SLC1A1 (0.50) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL7850044 0.78 TSHR (0.43) SLC1A3SLC1A2SLC1A1MEN1KMT2A
SCHEMBL14118736 0.78 BCHE (0.46) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL6800327 0.78 ALDH1A1 (0.43) SLC1A3SLC1A2SLC1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9586883-B2 Aldehyde-selective wacker-type oxidation of unbiased alkenes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-03-07 US disclosed
CN-101180272-B Organic compound and method for producing radioactive halogen-labeled organic compound using same NIHON MEDIPHYSICS CO LTD 2012-04-25 CN disclosed
CN-101180272-A Novel organic compound and method for producing radioactive halogen-labeled organic compound using same NIHON MEDIPHYSICS CO LTD (JP) 2008-05-14 CN disclosed