SCHEMBL28285993

SCHEMBL28285993

NC(CCC=O)OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 6/20 0.50
SLC1A3 P43003 5/20 0.50
SLC1A2 P43004 5/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 1/20 0.50
TACR1 P25103 2/20 0.40
EPHX1 P07099 1/20 0.39
IDO1 P14902 1/20 0.39
AGXT P21549 1/20 0.38
TSHR P16473 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SRC P12931 1/20 0.37
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18595449 0.79 SLC1A3 (0.42) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL11027935 0.78 SLC1A3 (0.47) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL16177726 0.78 CHRNB2 (0.46) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL16177521 0.77 SLC1A3 (0.41) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL9980202 0.77 SLC1A1 (0.41) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL16993409 0.77 SLC1A1 (0.51) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL10791168 0.77 SLC1A3 (0.46) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL9066639 0.77 SLC1A3 (0.46) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL8043274 0.77 SLC1A3 (0.46) SLC1A1SLC1A3SLC1A2MEN1CYP1A2
SCHEMBL14517178 0.76 KMT2A (0.49) SLC1A1SLC1A3SLC1A2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641900-A Chelate compound 通用电气医疗集团股份有限公司 2019-04-16 CN disclosed