Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073734 | 0.92 | PKM (0.71) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL3279437 | 0.90 | PKM (0.57) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL28277569 | 0.85 | PKM (0.62) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL17058903 | 0.84 | ACE2 (0.53) | PKMPOLBHTTALDH1A1KMT2A | |
| SCHEMBL23764853 | 0.82 | PKM (0.50) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL30426875 | 0.82 | PKM (0.50) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL28572184 | 0.82 | ALDH1A1 (0.49) | PKMPOLBHTTALDH1A1KMT2A | |
| SCHEMBL26493365 | 0.82 | PKM (0.46) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL24075452 | 0.82 | PKM (0.50) | PKMPOLBHSD17B1HTTALDH1A1 | |
| SCHEMBL1909365 | 0.80 | PKM (0.61) | PKMPOLBHSD17B1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978166-A | Preparation method of 3-ethyl-4-hydroxymethyl acetophenone | 南京康德祥医药科技有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-111405897-A | Process for the preparation of siponimod, its salts and solid forms | 雷迪博士实验室有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-109456156-A | A method of preparing 3- ethyl -4- methylol acetophenone | 荆门医药工业技术研究院 | 2019-03-12 | — | — | CN | claimed |
| CN-122070130-A | S1PR4 modulator compounds for myopathy treatment and uses thereof | 生元泽通(上海)医药有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122029146-A | S1PR4 modulator compounds for the treatment of autoimmune diseases and uses thereof | 生元泽通(上海)医药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4673126-A1 | COMPOSITIONS AND METHODS OF USE THEREOF | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-4192809-B1 | PROCESS FOR THE PREPARATION OF A KEY INTERMEDIATE OF SIPONIMOD | OLON SPA (IT) | 2025-09-03 | — | — | EP | disclosed |
| WO-2025077706-A1 | S1PR4 REGULATOR COMPOUND FOR MUSCLE DISEASE TREATMENT AND APPLICATION THEREOF | 华东师范大学 | 2025-04-17 | — | — | WO | disclosed |
| WO-2025077707-A1 | S1PR4 REGULATOR COMPOUND FOR AUTOIMMUNE DISEASE TREATMENT AND APPLICATION THEREOF | 华东师范大学 | 2025-04-17 | — | — | WO | disclosed |
| CN-119775186-A | S1PR4 modulator compounds for myopathy treatment and uses thereof | 华东师范大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775185-A | S1PR4 modulator compounds for the treatment of autoimmune diseases and uses thereof | 华东师范大学 | 2025-04-08 | — | — | CN | disclosed |
| EP-2809645-A1 | PROCESS FOR PREPARING N-(4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXY)-ACETIMIDIC ACID ETHYL ESTER | Novartis AG (CH) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013113915-A1 | PROCESS FOR PREPARING N-(4-CYCLOHEXYL-3-TRIFLUOROMETHYL-BENZYLOXY)-ACETIMIDIC ACID ETHYL ESTER | NOVARTIS AG (CH) | 2013-08-08 | — | — | WO | disclosed |
| EP-2514743-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2012-10-24 | — | — | EP | disclosed |
| US-7939519-B2 | Immunosuppresant compounds and compositions | NOVARTIS AG (CH) | 2011-05-10 | — | — | US | disclosed |
| US-20090036423-A1 | IMMUNOSUPPRESANT COMPOUNDS AND COMPOSITIONS | NOVARTIS PHARMACEUTICALS CORPORATION | 2009-02-05 | — | — | US | disclosed |
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | disclosed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | disclosed |
| US-20050014728-A1 | Immunosuppressant compounds and compositions | IRM LLC | 2005-01-20 | — | — | US | disclosed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014728-A1 | Immunosuppressant compounds and compositions | ICOS, EDNRA, NFATC1 | PKM 4392/4885POLB 4839/4885HSD17B1 2234/4885 |
| US-20090036423-A1 | IMMUNOSUPPRESANT COMPOUNDS AND COMPOSITIONS | EDNRA, NFATC1, FCGR1A | PKM 4525/4885POLB 4730/4885HSD17B1 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.