SCHEMBL1859769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1861053	0.90	TLR4 (0.43)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1862876	0.90	TLR4 (0.39)	TLR4KMT2ALMNAHPGDRECQL
	SCHEMBL1866081	0.90	TLR4 (0.42)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1863950	0.89	TLR4 (0.44)	TLR4KMT2AHPGDRECQLALDH1A1
	SCHEMBL1866325	0.89	TLR4 (0.49)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1859103	0.89	TLR4 (0.42)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1866089	0.89	KDM4E (0.42)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1862805	0.89	TLR4 (0.50)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1867851	0.89	TLR4 (0.42)	TLR4TSHRKDM4EHSD17B10KMT2A
	SCHEMBL1865403	0.88	TLR4 (0.40)	TLR4TSHRKDM4EHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.