SCHEMBL1866325

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1866369	0.90	TLR4 (0.46)	TLR4TSHRLMNAMAPTSMN1; SMN2
	SCHEMBL1861053	0.90	TLR4 (0.43)	TLR4TSHRLMNAMAPTHSD17B10
	SCHEMBL1866081	0.90	TLR4 (0.42)	TLR4TSHRLMNASMN1; SMN2HSD17B10
	SCHEMBL1864126	0.89	TLR4 (0.54)	TLR4TSHRLMNAHSD17B10KDM4E
	SCHEMBL1862365	0.89	TLR4 (0.53)	TLR4TSHRHSD17B10KDM4E
	SCHEMBL1863967	0.89	TLR4 (0.55)	TLR4THRBHSD17B10L3MBTL1
	SCHEMBL1865592	0.89	TLR4 (0.49)	TLR4TSHRLMNAMAPTSMN1; SMN2
	SCHEMBL1859769	0.89	TLR4 (0.42)	TLR4TSHRLMNASMN1; SMN2HSD17B10
	SCHEMBL1867851	0.89	TLR4 (0.42)	TLR4TSHRLMNASMN1; SMN2HSD17B10
	SCHEMBL1862805	0.89	TLR4 (0.50)	TLR4TSHRLMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.