Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889924 | 0.83 | CA2 (0.38) | CA2POLBKMT2AMEN1GABRA1 | |
| SCHEMBL8421248 | 0.81 | CA2 (0.50) | CA2GABRA1GABRB2MAPTTDP1 | |
| SCHEMBL4079663 | 0.74 | POLB (0.50) | CA2POLBKMT2AMEN1MAPT | |
| SCHEMBL6941036 | 0.74 | GABRA1 (0.52) | CA2GABRA1GABRB2TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2861569 | 0.73 | POLB (0.49) | CA2POLBKMT2AMEN1MAPT | |
| SCHEMBL19532816 | 0.72 | CA2 (0.41) | CA2POLBKMT2AMEN1GABRA1 | |
| SCHEMBL2809352 | 0.72 | CA2 (0.41) | CA2GABRA1GABRB2TDP1ALDH1A1 | |
| SCHEMBL22928093 | 0.72 | CA2 (0.41) | CA2POLBKMT2AMEN1GABRA1 | |
| SCHEMBL5486786 | 0.72 | CA2 (0.64) | CA2POLBKMT2AMEN1GABRA1 | |
| SCHEMBL2815255 | 0.72 | ALDH1A1 (0.56) | CA2GABRA1GABRB2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526102-B1 | Inhibitors of PI3 kinase | FUNDACIÓN CENTRO NAC DE INVESTIG ONCOLÓGICAS CARLOS III (ES) | 2017-03-08 | — | — | EP | disclosed |