Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26072111 | 0.86 | LMNA (0.44) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL27957734 | 0.86 | PDE4B (0.50) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL4274830 | 0.85 | PDE4B (0.44) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL27493715 | 0.84 | ESR2 (0.48) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL7649546 | 0.83 | PDE4B (0.43) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL2858581 | 0.82 | PDE4B (0.39) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL30058203 | 0.82 | MAPT (0.56) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL3680700 | 0.82 | MAPT (0.56) | HTTLMNAMEN1MAPTKMT2A | |
| SCHEMBL3061032 | 0.80 | CA1 (0.48) | HTTLMNAPDE4BPDE4APDE4C | |
| SCHEMBL28220956 | 0.80 | HTT (0.47) | HTTPDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046862-B1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | CA NAT RESEARCH COUNCIL (CA) | 2013-02-13 | — | — | EP | disclosed |
| US-7947800-B2 | Poly(aryl ether) with pendent sulfonic acid phenyl groups | NATIONAL RESEARCH COUNCIL OF CANADA | 2011-05-24 | — | — | US | disclosed |
| US-7615650-B2 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-11-10 | — | — | US | disclosed |
| US-20090203806-A1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2009-08-13 | — | — | US | disclosed |
| EP-2046862-A1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | National Research Council of Canada (CA) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008009102-A1 | POLY(ARYL ETHER) WITH PENDENT SULFONIC ACID PHENYL GROUPS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-01-24 | — | — | WO | disclosed |
| US-20070179304-A1 | Process for producing chroman compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1710239-A1 | PROCESS FOR PRODUCING CHROMAN COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179304-A1 | Process for producing chroman compound | TAF9, TAF1, CHD1 | HTT 4262/4885LMNA 1993/4885PDE4B 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.