Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979185 | 0.85 | S1PR3 (0.49) | — | |
| SCHEMBL15042602 | 0.85 | HDAC1 (0.36) | NR1H4SIGMAR1DAGLAFAAHCES1 | |
| SCHEMBL18601662 | 0.80 | SIGMAR1 (0.40) | SIGMAR1BCHE | |
| SCHEMBL12760665 | 0.80 | PLAU (0.38) | NR1H4SIGMAR1SMN1; SMN2BCHE | |
| SCHEMBL15022995 | 0.71 | C5AR1 (0.40) | SIGMAR1FAAHCES1BCHE | |
| SCHEMBL18601666 | 0.71 | SLC6A9 (0.39) | SIGMAR1CES1BCHE | |
| SCHEMBL15023492 | 0.70 | SIGMAR1 (0.44) | SIGMAR1BCHE | |
| SCHEMBL1979687 | 0.68 | SIGMAR1 (0.41) | SIGMAR1BCHE | |
| SCHEMBL18601655 | 0.68 | C5AR1 (0.39) | SIGMAR1SMN1; SMN2BCHE | |
| SCHEMBL18601659 | 0.67 | S1PR2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504323-B1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN INC (US) | 2017-03-15 | — | — | EP | claimed |