Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL18604024 | 0.94 | MAOA (0.48) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604231 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604255 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604235 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604193 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604244 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604177 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604120 | 0.93 | HRH1 (0.47) | MAOACHRNA7CHRNA10CHRNA9HRH1 | |
| Bromide SCHEMBL18604097 | 0.88 | TAAR1 (0.45) | CHKAHTR2ACYP2A6 | |
| Bromide SCHEMBL19741468 | 0.81 | KMT2A (0.42) | CHRNA7CHRNA10CHRNA9CHKAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025070397-A1 | ETHYLENE GLYCOL, POLYESTER, POLYESTER PELLETS, MOLDED ARTICLE, FILM, FIBERS, FIBER ARTICLE, MOLDED ARTICLE, PREFORM, POLYESTER FILM, LAMINATED FILM, LAMINATE, AND PACKAGE | 大日本印刷株式会社 | 2025-04-03 | — | — | WO | disclosed |
| US-10550488-B2 | Reduction catalyst, reduction reactor and reduction method | KABUSHIKI KAISHA TOSHIBA (JP) | 2020-02-04 | — | — | US | disclosed |
| US-10465303-B2 | Producing system of reduction product | KABUSHIKI KAISHA TOSHIBA (JP) | 2019-11-05 | — | — | US | disclosed |
| US-10308574-B2 | Reduction catalyst and chemical reactor | KABUSHIKI KAISHA TOSHIBA (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20180073154-A1 | REDUCTION CATALYST, REDUCTION REACTOR AND REDUCTION METHOD | KABUSHIKI KAISHA TOSHIBA (JP) | 2018-03-15 | — | — | US | disclosed |
| EP-3293288-A1 | REDUCTION CATALYST, REDUCTION REACTOR AND REDUCTION METHOD | Kabushiki Kaisha Toshiba (JP) | 2018-03-14 | — | — | EP | disclosed |
| US-20170369405-A1 | REDUCTION CATALYST AND CHEMICAL REACTOR | KABUSHIKI KAISHA TOSHIBA (JP) | 2017-12-28 | — | — | US | disclosed |
| US-20170073827-A1 | PRODUCING SYSTEM OF REDUCTION PRODUCT | KABUSHIKI KAISHA TOSHIBA (JP) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308574-B2 | Reduction catalyst and chemical reactor | MPO, NOX4, IDH2 | CHKA 3577/4885MAOA 255/4885CHRNA7 3494/4885 |
| US-20170369405-A1 | REDUCTION CATALYST AND CHEMICAL REACTOR | MPO, NOX4, IDH2 | CHKA 3577/4885MAOA 255/4885CHRNA7 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.