Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | METAP1 | P53582 | 7/20 | 0.51 |
| ▸ | METAP2 | P50579 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370046 | 0.91 | L3MBTL1 (0.63) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL20665658 | 0.83 | L3MBTL1 (0.54) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL20371378 | 0.81 | KDM4E (0.59) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL11036761 | 0.80 | KDM4E (0.68) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL12143473 | 0.77 | METAP1 (0.73) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL4482806 | 0.76 | L3MBTL1 (0.50) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL16876611 | 0.76 | L3MBTL1 (0.53) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL322756 | 0.74 | KDM4E (1.00) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL29354466 | 0.74 | KDM4E (1.00) | L3MBTL1KDM4EALOX15TDP1METAP1 | |
| SCHEMBL1704624 | 0.74 | KDM4E (0.76) | L3MBTL1KDM4EALOX15TDP1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170071940-A1 | Methionine Aminopeptidase Inhibitors for Treating Infectious Diseases | TEXAS SOUTHERN UNIVERSITY (US) | 2017-03-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170071940-A1 | Methionine Aminopeptidase Inhibitors for Treating Infectious Diseases | METAP1, DNPEP, METAP2 | L3MBTL1 1148/4885KDM4E 2771/4885ALOX15 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.