Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336139 | 0.84 | HTR7 (0.56) | HTR7MAPTALDH1A1KDM4EXDH | |
| SCHEMBL7250352 | 0.81 | HTR7 (0.51) | HTR7MAPTALDH1A1KDM4EXDH | |
| SCHEMBL18607551 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1MAPK1HPGDTDP1 | |
| SCHEMBL2955704 | 0.80 | ALDH1A1 (0.54) | HTR7MAPTALDH1A1KDM4EXDH | |
| SCHEMBL10134271 | 0.78 | HTR7 (0.51) | HTR7MAPTALDH1A1KDM4EXDH | |
| SCHEMBL18607586 | 0.78 | RAB9A (0.43) | MAPTALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL11188343 | 0.78 | HTR7 (0.54) | HTR7MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL18607708 | 0.76 | ALDH1A1 (0.51) | MAPTALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL27530424 | 0.76 | MAPT (0.67) | HTR7MAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL5147211 | 0.75 | MAPT (0.54) | HTR7MAPTALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017038870-A1 | UREA DERIVATIVE AND USE THEREOF | 東レ株式会社 | 2017-03-09 | — | — | WO | disclosed |