SCHEMBL1860801

SCHEMBL1860801

NOC(=O)/C=C/c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.59
LMNA P02545 3/20 0.59
ALDH1A1 P00352 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
PLIN1 O60240 2/20 0.59
RECQL P46063 2/20 0.59
PLIN5 Q00G26 2/20 0.59
ABHD5 Q8WTS1 2/20 0.59
TNKS O95271 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC10 Q969S8 1/20 0.59
HDAC11 Q96DB2 1/20 0.59
TNKS2 Q9H2K2 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1860803 1.00 MAPT (0.59) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
Aniline SCHEMBL4258946 0.93 CYP1B1 (0.57) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
SCHEMBL21803794 0.83 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
SCHEMBL869266 0.83 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
SCHEMBL775716 0.83 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
SCHEMBL9247555 0.83 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
SCHEMBL869265 0.83 MAPT (0.64) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
E-Methyl Cinnamate SCHEMBL29834291 0.82 CA12 (0.67) MAPTLMNAALDH1A1SMN1; SMN2HDAC3
SCHEMBL5606482 0.82 CA12 (0.67) HCAR2CYP2D6CYP2C9F3RAB9A
SCHEMBL209340 0.81 LMNA (0.61) MAPTLMNAALDH1A1SMN1; SMN2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103232400-B Method for preparing quinazoline-2-thioketone UNIV SOOCHOW 2015-01-21 CN claimed
CN-114946033-B Ultra-high density quantum dot color converter 德遁公司 2025-02-14 CN disclosed
CN-106795327-B Resin composition and optical compensation film using the same 东曹株式会社 2019-08-30 CN disclosed
CN-108778237-A Moisturizing personal care compositions containing monodisperse phytoglycogen nanoparticles and additional polysaccharides 奇迹连结生物技术公司 2018-11-09 CN disclosed
CN-108250152-A It is a kind of with the 3,4- dihydroquinazoline derivatives and its synthetic method of antibacterial activity and application 浙江师范大学 2018-07-06 CN disclosed
CN-108101866-A It is a kind of with the 1,3- benzothiazine derivatives and its synthetic method of antibacterial activity and application 浙江师范大学 2018-06-01 CN disclosed
CN-107698537-A It is a kind of with the benzothiazine derivatives of 4H 1,3 and its synthetic method of antibacterial activity and application 浙江师范大学 2018-02-16 CN disclosed
CN-107406770-A Metallomesogen dyestuff 哥兹有限公司 2017-11-28 CN disclosed
CN-106795327-A Resin composition and optical compensation film using the same 东曹株式会社 2017-05-31 CN disclosed
CN-103787992-B N, N-disubstituted benzene nitrogen heterocyclic-2-aminated compounds and uses thereof EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-04-20 CN disclosed
CN-1589258-A Novel beta -phenyl- alpha -oxysubstituted propionic derivatives: process for their preparation and their use in the preparation of pharmaceutically important compounds REDDY S LAB LTD (IN) 2005-03-02 CN disclosed
EP-1436247-A1 NOVEL-BETA-PHENYL-ALPHA-OXYSUBSTITUTED PROPIONIC DERIVATIVES: PROCESS FOR ITS PREPARATION AND THEIR USE IN THE PREPARATION OF PHARMACEUTICALLY IMPORTANT COMPOUNDS Dr. Reddy's Laboratories Ltd. (IN) 2004-07-14 EP disclosed
EP-1436268-A1 BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dr. Reddy's Laboratories Ltd. (IN) 2004-07-14 EP disclosed
WO-2003033481-A1 BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2003-04-24 WO disclosed
WO-2003033456-A1 NOVEL β-PHENYL-α-OXYSUBSTITUTED PROPIONIC DERIVATIVES: PROCESS FOR ITS PREPARATION AND THEIR USE IN THE PREPARATION OF PHARMACEUTICALLY IMPORTANT COMPOUNDS DR. REDDY'S LABORATORIES LTD. (IN) 2003-04-24 WO disclosed
CN-1098278-C Cinnamic acid derivative SEIKAGAKU KOGYO CO LTD (JP) 2003-01-08 CN disclosed
CN-1090637-C Crosslinked cinnamic acid hyaluronic acid derivatives and process for producing the same SEIKAGAKU KOGYO CO LTD (JP) 2002-09-11 CN disclosed
US-6329546-B1 FOR INVESTIGATING THE MECHANISM OF ACTION OF A PHYSIOLOGICALLY ACTIVE AMINO ACID COMPOUND SUCH AS GLUTAMIC ACID IN AN ORGANISM LABORATORY OF MOLECULAR BIOPHOTONICS (JP) 2001-12-11 US disclosed
CN-1245812-A Cinnamic acid derivative SEIKAGAKU KOGYO CO LTD (JP) 2000-03-01 CN disclosed
CN-1133834-A cinnamic acid derivatives SEIKAGAKU KOGYO CO LTD (JP) 1996-10-23 CN disclosed