Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.80 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023783 | 0.91 | HRH1 (0.79) | HRH1KCNH2CYP2J2 | |
| SCHEMBL18609138 | 0.90 | HRH1 (0.80) | HRH1KCNH2CYP2J2 | |
| SCHEMBL18609370 | 0.89 | HRH1 (0.78) | HRH1KCNH2CYP2J2 | |
| SCHEMBL20306199 | 0.89 | HRH1 (1.00) | HRH1KCNH2CYP2J2 | |
| SCHEMBL18609333 | 0.89 | HRH1 (0.78) | HRH1KCNH2CYP2J2 | |
| SCHEMBL17023752 | 0.88 | HRH1 (0.80) | HRH1KCNH2CYP2J2 | |
| SCHEMBL18609072 | 0.87 | HRH1 (0.75) | HRH1KCNH2CYP2J2 | |
| SCHEMBL18609381 | 0.87 | HRH1 (0.79) | HRH1KCNH2CYP2J2 | |
| SCHEMBL18609237 | 0.87 | HRH1 (1.00) | HRH1KCNH2CYP2J2 | |
| SCHEMBL17023779 | 0.84 | HRH1 (0.80) | HRH1KCNH2CYP2J2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004701-B2 | Methods and compositions for treating infection | UNIVERSITY OF ROCHESTER (US) | 2018-06-26 | — | — | US | disclosed |
| US-20170065540-A1 | METHODS AND COMPOSITIONS FOR TREATING INFECTION | UNIVERSITY OF ROCHESTER (US) | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065540-A1 | METHODS AND COMPOSITIONS FOR TREATING INFECTION | MMP8, IFNG, MPO | HRH1 1562/4885KCNH2 1413/4885CYP2J2 2123/4885 |
| US-10004701-B2 | Methods and compositions for treating infection | MMP8, IFNG, MPO | HRH1 1562/4885KCNH2 1413/4885CYP2J2 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.