Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959038 | 1.00 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C9GAAHSD17B10 | |
| SCHEMBL14959021 | 0.91 | ALDH1A1 (0.56) | ALDH1A1CYP1A2CYP2C9GAADRD2 | |
| SCHEMBL14960573 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9LMNATSHR | |
| SCHEMBL13060130 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9LMNATSHR | |
| SCHEMBL18532596 | 0.89 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9LMNATSHR | |
| SCHEMBL20879776 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C9GAAHSD17B10 | |
| SCHEMBL25133167 | 0.88 | TRPM8 (0.46) | ALDH1A1CYP1A2CYP2C9GAAHSD17B10 | |
| SCHEMBL13060133 | 0.88 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C9GAAHSD17B10 | |
| SCHEMBL12176191 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C9GAAHSD17B10 | |
| SCHEMBL18609697 | 0.88 | TRPM8 (0.46) | ALDH1A1CYP1A2CYP2C9GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065604-A1 | C5aR ANTAGONISTS | CHEMOCENTRYX, INC. | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065604-A1 | C5aR ANTAGONISTS | C5AR1, C5AR2, C3AR1 | ALDH1A1 2882/4885CYP1A2 2361/4885CYP2C9 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.