Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18609476 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL14959038 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL20879814 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL18532609 | 0.85 | TRPM8 (0.44) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL18790113 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL24016940 | 0.84 | UBE2M (0.52) | ALDH1A1MAPTSMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL18532607 | 0.84 | KMT2A (0.53) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL13060052 | 0.83 | CYP1A2 (0.39) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL12176605 | 0.83 | CYP1A2 (0.39) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL24016937 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078658-B1 | C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2019-04-10 | — | — | EP | disclosed |