Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.46 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17805431 | 0.90 | GPBAR1 (0.49) | RIPK1GPBAR1SCD5TRPC3TRPC6 | |
| SCHEMBL18532583 | 0.90 | GPBAR1 (0.49) | RIPK1GPBAR1SCD5TRPC3TRPC6 | |
| SCHEMBL26006171 | 0.84 | PREP (0.46) | RIPK1GRM5GPBAR1LMNAPREP | |
| SCHEMBL24045646 | 0.81 | GPBAR1 (0.42) | GPBAR1TRPC3TRPC6LMNAPREP | |
| SCHEMBL22043704 | 0.81 | GPBAR1 (0.42) | GPBAR1TRPC3TRPC6LMNAPREP | |
| SCHEMBL30103461 | 0.81 | GPBAR1 (0.42) | GPBAR1TRPC3TRPC6LMNAPREP | |
| SCHEMBL17805416 | 0.80 | GPBAR1 (0.41) | GPBAR1TRPC3TRPC6PREP | |
| SCHEMBL24016955 | 0.80 | RAB9A (0.41) | GPBAR1TRPC3TRPC6PREP | |
| SCHEMBL27341297 | 0.79 | PRMT5 (0.49) | RIPK1GRM5SCD5ROCK2TRPC3 | |
| SCHEMBL18801701 | 0.78 | SMN1; SMN2 (0.41) | GPBAR1LMNAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065604-A1 | C5aR ANTAGONISTS | CHEMOCENTRYX, INC. | 2017-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170065604-A1 | C5aR ANTAGONISTS | C5AR1, C5AR2, C3AR1 | RIPK1 3510/4885GRM5 824/4885GPBAR1 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.