Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628967 | 0.65 | CHIT1 (0.60) | ALDH1A1 | |
| SCHEMBL23682775 | 0.61 | L3MBTL3 (1.00) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL1813299 | 0.60 | — | — | |
| SCHEMBL26117153 | 0.60 | L3MBTL3 (0.52) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL26112589 | 0.60 | L3MBTL3 (0.52) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL3195988 | 0.59 | L3MBTL3 (0.43) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL11942150 | 0.59 | L3MBTL3 (0.43) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL1543190 | 0.59 | L3MBTL3 (0.43) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL488798 | 0.59 | L3MBTL3 (0.48) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL12714589 | 0.59 | L3MBTL3 (0.43) | L3MBTL1L3MBTL3MBTD1TP53BP1L3MBTL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |
| WO-2017037670-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2017-03-09 | — | — | WO | disclosed |