Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 12/20 | 0.60 |
| ▸ | CHIA | Q9BZP6 | 9/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455907 | 0.82 | GAA (0.69) | CHIT1CHIAGAAKCNH2MAPT | |
| SCHEMBL18610008 | 0.81 | CHIT1 (0.60) | CHIT1CHIAGAAKCNH2MAPT | |
| SCHEMBL9793471 | 0.81 | GAA (0.67) | CHIT1CHIAGAAKCNH2MAPT | |
| SCHEMBL1994355 | 0.70 | GAA (1.00) | CHIT1CHIAGAAKCNH2MAPT | |
| SCHEMBL9793417 | 0.70 | GAA (0.62) | CHIT1CHIAGAAMAPTALDH1A1 | |
| SCHEMBL4257753 | 0.67 | L3MBTL1 (0.50) | KCNH2ALDH1A1 | |
| SCHEMBL31387185 | 0.66 | GAA (0.56) | CHIT1CHIAGAAKCNH2MAPT | |
| SCHEMBL31214493 | 0.65 | GAA (0.63) | CHIT1CHIAGAAKCNH2MAPT | |
| SCHEMBL18609788 | 0.65 | L3MBTL1 (0.43) | ALDH1A1 | |
| SCHEMBL14853335 | 0.63 | L3MBTL3 (0.50) | KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344616-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-01-09 | — | — | EP | disclosed |