Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 6/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28228051 | 0.75 | CHIT1 (0.50) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL18586831 | 0.74 | CMA1 (0.44) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL18577325 | 0.74 | CMA1 (0.44) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL18586428 | 0.69 | CHIA (0.64) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| SCHEMBL18586427 | 0.69 | CHIA (0.64) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL18577386 | 0.68 | CHIA (0.63) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL18577385 | 0.68 | CHIA (0.63) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| SCHEMBL26704123 | 0.68 | L3MBTL1 (0.40) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| SCHEMBL18577265 | 0.67 | CHIT1 (0.43) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL18577267 | 0.67 | CHIT1 (0.43) | CHIT1CHIAL3MBTL1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037670-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2017-03-09 | — | — | WO | disclosed |