Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 2/20 | 0.50 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933242 | 0.88 | CA1 (0.54) | CA1CA2CA4CA9 | |
| SCHEMBL18586428 | 0.77 | CHIA (0.64) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| SCHEMBL18586427 | 0.77 | CHIA (0.64) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL18577385 | 0.76 | CHIA (0.63) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| Hydrochloric Acid SCHEMBL18577386 | 0.76 | CHIA (0.63) | CHIT1CHIAL3MBTL1FPR2PROKR1 | |
| SCHEMBL18610263 | 0.75 | CHIT1 (0.42) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL18577080 | 0.74 | CHIT1 (0.61) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL18586810 | 0.74 | CHIT1 (0.61) | CHIT1CHIAL3MBTL1MEN1POLB | |
| SCHEMBL25154742 | 0.74 | CA1 (0.48) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL25154276 | 0.74 | CA1 (0.48) | MEN1POLBKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290863-A | Substituted aminotriazoles useful as human chitinase inhibitors | 昂科艾伦迪治疗法公司 | 2018-07-17 | — | — | CN | disclosed |