Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454792 | 0.79 | PARP15 (0.62) | PARP10MAOBPARP15SIRT2NR4A2 | |
| SCHEMBL7907691 | 0.79 | MAOB (0.73) | PARP10MAOBPARP15SIRT2NR4A2 | |
| SCHEMBL162815 | 0.78 | PARP10 (0.60) | PARP10MAOBPARP15SIRT2MAPT | |
| SCHEMBL10367941 | 0.78 | LTB4R (0.61) | MAOBLTB4RLTB4R2NR4A2 | |
| SCHEMBL11091059 | 0.77 | EGFR (0.49) | PARP10MAOBSIRT2LTA4HKDM4E | |
| SCHEMBL4930554 | 0.75 | PARP10 (0.60) | PARP10MAOBPARP15SIRT2MAPT | |
| SCHEMBL9662974 | 0.75 | MEN1 (0.50) | PARP10MAOBPARP15SIRT2LTB4R | |
| SCHEMBL6140955 | 0.75 | PARP15 (0.75) | PARP10MAOBPARP15SIRT2PARP14 | |
| SCHEMBL4693369 | 0.74 | FFAR1 (0.49) | PARP10MAOBPARP15PARP14MAPT | |
| SCHEMBL2206195 | 0.73 | CYP4F2 (0.66) | MAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017042099-A1 | EFFLUX-PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | BASILEA PHARMACEUTICA AG (CH) | 2017-03-16 | — | — | WO | disclosed |