Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21779399 | 0.84 | AXL (0.41) | SIGMAR1TMEM97DRD4CARM1PRMT6 | |
| SCHEMBL18611467 | 0.82 | HRH3 (0.42) | SIGMAR1TMEM97DRD4GABRPGABRD | |
| SCHEMBL18612195 | 0.80 | GABRP (0.42) | SIGMAR1TMEM97DRD4GABRPGABRD | |
| SCHEMBL18611755 | 0.79 | CHRNA3 (0.40) | SIGMAR1TMEM97DRD4GABRPGABRD | |
| SCHEMBL18615720 | 0.78 | CARM1 (0.43) | SIGMAR1TMEM97DRD4CARM1PRMT6 | |
| SCHEMBL18615812 | 0.77 | HRH3 (0.60) | HRH3 | |
| SCHEMBL4962479 | 0.77 | CARM1 (0.48) | SIGMAR1TMEM97CARM1PRMT6OPRM1 | |
| SCHEMBL7062835 | 0.77 | DRD4 (0.58) | SIGMAR1TMEM97DRD4HRH3NAAA | |
| SCHEMBL8457459 | 0.76 | CARM1 (0.46) | SIGMAR1TMEM97DRD4CARM1PRMT6 | |
| SCHEMBL8449011 | 0.76 | DRD4 (0.56) | SIGMAR1TMEM97DRD4HRH3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |