Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 9/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 9/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615720 | 0.98 | CARM1 (0.43) | CARM1PRMT6OPRM1OPRL1NPC1 | |
| SCHEMBL18611721 | 0.93 | CARM1 (0.46) | CARM1PRMT6OPRM1OPRL1NPC1 | |
| SCHEMBL4962479 | 0.90 | CARM1 (0.48) | CARM1PRMT6OPRM1OPRL1NAAA | |
| SCHEMBL11587452 | 0.85 | NAAA (0.54) | CARM1PRMT6OPRM1OPRL1NPC1 | |
| SCHEMBL1837908 | 0.82 | NPC1 (0.46) | CARM1PRMT6OPRM1OPRL1NPC1 | |
| SCHEMBL18615830 | 0.82 | NAAA (0.51) | CARM1PRMT6OPRM1OPRL1NAAA | |
| SCHEMBL1837027 | 0.82 | NPC1 (0.46) | CARM1PRMT6OPRM1OPRL1NPC1 | |
| SCHEMBL1836248 | 0.82 | NPC1 (0.46) | CARM1PRMT6OPRM1OPRL1NPC1 | |
| SCHEMBL14394540 | 0.82 | SMN1; SMN2 (0.43) | CARM1PRMT6OPRM1OPRL1NAAA | |
| SCHEMBL22454181 | 0.81 | NAAA (0.56) | CARM1PRMT6NPC1RAB9ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058380-A1 | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI-AVENTIS (FR) | 2008-03-06 | — | — | US | disclosed |
| US-7288659-B2 | Acylaminothiazole derivatives, their preparation and therapeutic use | SANOFI-AVENTIS (FR) | 2007-10-30 | — | — | US | disclosed |
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058380-A1 | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | PARK7, ACAT1, APP | CARM1 1092/4885PRMT6 227/4885OPRM1 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.