Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | DDO | Q99489 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954688 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL5227513 | 0.98 | KDM4E (0.57) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| SCHEMBL51830 | 0.85 | HCAR2 (0.70) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| SCHEMBL26680771 | 0.82 | NPC1 (0.51) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL7661020 | 0.82 | HCAR2 (0.67) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| Fluoride SCHEMBL21331909 | 0.82 | HCAR2 (0.67) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| SCHEMBL19987838 | 0.82 | HCAR2 (0.67) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| Bromide SCHEMBL21332093 | 0.82 | HCAR2 (0.67) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL7124062 | 0.82 | HCAR2 (0.67) | KDM4EALDH1A1HCAR2POLBMEN1 | |
| Hydrochloric Acid SCHEMBL1117746 | 0.82 | HCAR2 (0.67) | KDM4EALDH1A1HCAR2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974758-B | Carboxymethyl ketone compound and preparation method thereof | 生物岛实验室 | 2025-06-10 | — | — | CN | claimed |
| CN-120004634-A | Low-dielectric-constant aluminum nitride ceramic substrate and preparation method thereof | 军瓷电子材料河北有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-119158012-B | Antigen targeting peptide nano micelle and application thereof | 浙江省肿瘤医院 | 2025-03-18 | — | — | CN | claimed |
| CN-119158012-A | Antigen targeting peptide nano micelle and application thereof | 浙江省肿瘤医院 | 2024-12-20 | — | — | CN | claimed |
| US-12077680-B2 | Polishing composition, production method of the same, polishing method and a manufacturing method of a semiconductor substrate | FUJIMI INCORPORATED (JP) | 2024-09-03 | — | — | US | claimed |
| CN-115974758-A | Carboxymethyl ketone compound and preparation method thereof | 生物岛实验室 | 2023-04-18 | — | — | CN | claimed |
| US-20210301174-A1 | POLISHING COMPOSITION, PRODUCTION METHOD OF THE SAME, POLISHING METHOD AND A MANUFACTURING METHOD OF A SEMICONDUCTOR SUBSTRATE | FUJIMI INCORPORATED (JP) | 2021-09-30 | — | — | US | claimed |
| CN-113046734-A | Bivalent palladium complex solution and preparation method and application thereof | 上海天承化学有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-105646552-A | Zn(II) complex based on 5-hydroxynictinic acid and preparation method and application thereof | 天津师范大学 | 2016-06-08 | — | — | CN | claimed |
| US-20030125328-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-07-03 | — | — | US | claimed |
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-22 | — | — | US | claimed |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-05-08 | — | — | US | claimed |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-05-01 | — | — | US | claimed |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. | 2003-02-13 | — | — | US | claimed |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| EP-1115693-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | claimed |
| WO-2000018721-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| US-5430049-A | Treating hyperproliferative disorders | GAUT ZANE N (US) | 1995-07-04 | — | — | US | claimed |
| EP-0003663-A2 | Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-08-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125328-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | KDM4E 2831/4885ALDH1A1 2277/4885HCAR2 1015/4885 |
| US-20030096818-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | KDM4E 2831/4885ALDH1A1 2277/4885HCAR2 1015/4885 |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, LCAT, MTTP | KDM4E 3107/4885ALDH1A1 2079/4885HCAR2 1151/4885 |
| US-20030087905-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | KDM4E 2831/4885ALDH1A1 2277/4885HCAR2 1015/4885 |
| US-20030083331-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, LCAT | KDM4E 2831/4885ALDH1A1 2277/4885HCAR2 1015/4885 |
| US-20030032644-A1 | Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, MTTP, PCTP | KDM4E 1432/4885ALDH1A1 2611/4885HCAR2 822/4885 |
| US-20020165232-A1 | Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, PLTP | KDM4E 3603/4885ALDH1A1 2588/4885HCAR2 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.