Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15803621 | 0.91 | SMN1; SMN2 (0.38) | SMN1; SMN2USP2KDM4EALDH1A1KEAP1 | |
| SCHEMBL15802610 | 0.86 | SMN1; SMN2 (0.35) | SMN1; SMN2USP2KDM4EALDH1A1KEAP1 | |
| SCHEMBL15802639 | 0.84 | HRH3 (0.39) | SMN1; SMN2USP2KDM4EALDH1A1KEAP1 | |
| SCHEMBL1859823 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2USP2KDM4EALDH1A1KEAP1 | |
| SCHEMBL776376 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2USP2KDM4EALDH1A1KEAP1 | |
| SCHEMBL1995114 | 0.81 | HRH3 (0.33) | SMN1; SMN2ALDH1A1TDP1TSHRKCNH2 | |
| SCHEMBL2508441 | 0.81 | HRH3 (0.33) | SMN1; SMN2ALDH1A1TDP1TSHRKCNH2 | |
| SCHEMBL4071773 | 0.79 | — | — | |
| SCHEMBL538013 | 0.77 | CYP1A2 (0.34) | SMN1; SMN2ALDH1A1CXCR4CYP1A2CHRM2 | |
| SCHEMBL15802638 | 0.77 | USP2 (0.40) | SMN1; SMN2USP2KDM4EALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637600-B2 | Cross-linkable masses based on organosilicon compounds | WACKER CHEMIE AG (DE) | 2017-05-02 | — | — | US | claimed |
| US-10647822-B2 | Process for preparing organosilicon compounds containing organyloxy groups | WACKER CHEMIE AG (DE) | 2020-05-12 | — | — | US | disclosed |
| US-20180194902-A1 | PROCESS FOR PREPARING ORGANOSILICON COMPOUNDS CONTAINING ORGANYLOXY GROUPS | WACKER CHEMIE AG (DE) | 2018-07-12 | — | — | US | disclosed |
| US-9637600-B2 | Cross-linkable masses based on organosilicon compounds | WACKER CHEMIE AG (DE) | 2017-05-02 | — | — | US | disclosed |
| EP-2367868-B1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| US-8197591-B2 | Pearlescent pigments having a secondary coating comprising α-silanes and method for the production thereof | ECKART GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20110245377-A1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| EP-2367868-A1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | Wacker Chemie AG (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-1904587-B8 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING (ALPHA)-SILANES AND METHOD FOR THE PRODUCTION THEREOF | ECKART GMBH (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-1904587-B1 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCTION THEREOF | ECKART GMBH (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010072615-A1 | CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2010-07-01 | — | — | WO | disclosed |
| US-20090249979-A1 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF | ECKART GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| EP-1904587-A2 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING -SILANES AND METHOD FOR THE PRODUCITON THEREOF | Eckart GmbH (DE) | 2008-04-02 | — | — | EP | disclosed |
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| WO-2007098887-A2 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING α-SILANES AND METHOD FOR THE PRODUCITON THEREOF | ECKART GMBH (DE) | 2007-09-07 | — | — | WO | disclosed |
| EP-1473296-B1 | Organofunctional surface modified metal oxides | WACKER CHEMIE AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1473296-A1 | Organofunctional surface modified metal oxides | Wacker-Chemie GmbH (DE) | 2004-11-03 | — | — | EP | disclosed |