SCHEMBL2508441

SCHEMBL2508441

CO[Si](C)(CN1CCCCC1)OC

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.33
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
KCNH2 Q12809 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.31
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
PRMT8 Q9NR22 1/20 0.30
CHRM5 P08912 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995114 1.00 HRH3 (0.33) HRH3GAASMN1; SMN2KCNH2MEN1
SCHEMBL15802639 0.84 HRH3 (0.39) HRH3SMN1; SMN2ALDH1A1TDP1
SCHEMBL1861629 0.81 SMN1; SMN2 (0.40) HRH3SMN1; SMN2KCNH2ALDH1A1TDP1
SCHEMBL4071773 0.79
SCHEMBL329641 0.78 HRH3 (0.35) HRH3GAAMEN1KMT2AALDH1A1
SCHEMBL1230677 0.78 HRH3 (0.35) HRH3GAAMEN1KMT2AALDH1A1
SCHEMBL538013 0.77 CYP1A2 (0.34) SMN1; SMN2MEN1KMT2AALDH1A1CHRM5
SCHEMBL1230445 0.77 HRH3 (0.41) HRH3ALDH1A1CARM1PRMT6PRMT8
SCHEMBL2501931 0.77 HRH3 (0.31) HRH3
SCHEMBL1992740 0.77 HRH3 (0.31) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9637600-B2 Cross-linkable masses based on organosilicon compounds WACKER CHEMIE AG (DE) 2017-05-02 US claimed
US-9637600-B2 Cross-linkable masses based on organosilicon compounds WACKER CHEMIE AG (DE) 2017-05-02 US disclosed
EP-2367868-B1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2012-11-07 EP disclosed
US-20110245377-A1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2011-10-06 US disclosed