SCHEMBL776376

SCHEMBL776376

CO[Si](CN1CCOCC1)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
USP2 O75604 1/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 3/20 0.37
KEAP1 Q14145 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HSD17B10 Q99714 2/20 0.35
CXCR4 P61073 1/20 0.35
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
CYP1A2 P05177 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
HTR2A P28223 1/20 0.34
MAPK1 P28482 1/20 0.34
SCN1A P35498 1/20 0.34
HTR2B P41595 1/20 0.34
KCNH2 Q12809 1/20 0.34
SCN2A Q99250 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1859823 0.81 SMN1; SMN2 (0.40) SMN1; SMN2USP2KDM4EALDH1A1KEAP1
SCHEMBL1861629 0.81 SMN1; SMN2 (0.40) SMN1; SMN2USP2KDM4EALDH1A1KEAP1
SCHEMBL12802541 0.80 TDP1 (0.44) SMN1; SMN2KDM4EALDH1A1KEAP1TDP1
SCHEMBL2502895 0.80 CARM1 (0.32) HRH3
SCHEMBL25311709 0.80 ALDH1A1 (0.37) SMN1; SMN2USP2ALDH1A1TSHRCYP1A2
SCHEMBL329641 0.78 HRH3 (0.35) ALDH1A1TDP1TSHRHRH3HTT
SCHEMBL1230677 0.78 HRH3 (0.35) ALDH1A1TDP1TSHRHRH3HTT
SCHEMBL4069891 0.77
SCHEMBL787845 0.77 TSHR (0.38) SMN1; SMN2USP2KDM4EALDH1A1KEAP1
SCHEMBL15803621 0.77 SMN1; SMN2 (0.38) SMN1; SMN2USP2KDM4EALDH1A1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4157943-B1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2024-01-31 EP claimed
US-20230183427-A1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2023-06-15 US claimed
WO-2023099015-A1 PROCESS FOR PREPARING ORGANOSILICON COMPOUNDS CONTAINING ORGANYLOXY GROUPS WACKER CHEMIE AG (DE) 2023-06-08 WO claimed
EP-4157943-A1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS Wacker Chemie AG (DE) 2023-04-05 EP claimed
CN-115667405-A Crosslinkable substances based on organosilicon compounds 瓦克化学股份公司 2023-01-31 CN claimed
US-9637600-B2 Cross-linkable masses based on organosilicon compounds WACKER CHEMIE AG (DE) 2017-05-02 US claimed
US-12606576-B2 Method for producing nitrogen-containing organoxysilane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-04-21 US disclosed
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed
CN-113423766-B Crosslinkable compositions based on organosilicon compounds 瓦克化学股份公司 2024-10-01 CN disclosed
EP-4208509-B1 CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2024-02-28 EP disclosed
EP-4006042-B1 METHOD FOR PRODUCING NITROGEN-CONTAINING ORGANOXYSILANE COMPOUND SHINETSU CHEMICAL CO (JP) 2024-01-31 EP disclosed
EP-4157943-B1 CROSS-LINKABLE MASSES BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2024-01-31 EP disclosed
EP-1611141-B1 ORGANOSILYL FUNCTIONALIZED PARTICLES AND THE PRODUCTION THEREOF CONSORTIUM ELEKTROCHEM IND (DE) 2006-06-28 EP disclosed
US-20060020097-A1 Organosilyl functionalized particles and the production thereof CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2006-01-26 US disclosed
EP-1611141-A1 ORGANOSILYL FUNCTIONALIZED PARTICLES AND THE PRODUCTION THEREOF Consortium für elektrochemische Industrie GmbH (DE) 2006-01-04 EP disclosed
WO-2005108495-A2 MOISTURE CROSS-LINKING COMPOSITION CONTAINING ALKOXYSILYL FUNCTIONAL PARTICLES Consortium für elektrochemische Industrie GmbH (DE) 2005-11-17 WO disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed
WO-2004089961-A1 ORGANOSILYL FUNCTIONALIZED PARTICLES AND THE PRODUCTION THEREOF Consortium für elektrochemische Industrie GmbH (DE) 2004-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 SMN1; SMN2 1908/4885USP2 1718/4885KDM4E 2897/4885
US-12606576-B2 Method for producing nitrogen-containing organoxysilane compound HRH3, HRH4, H1-0 SMN1; SMN2 1338/4885USP2 3350/4885KDM4E 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.