SCHEMBL538013

SCHEMBL538013

CO[Si](C)(CN1CCNCC1)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CHRM2 P08172 1/20 0.34
SLC6A4 P31645 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
APOBEC3A P31941 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CXCR4 P61073 2/20 0.32
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
SIGMAR1 Q99720 2/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SOS1 Q07889 1/20 0.30
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4066940 0.83 CYP1A2 (0.34) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL538032 0.80 CYP1A2 (0.35) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL4061521 0.79 MEN1 (0.41) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL538138 0.79 SIGMAR1 (0.36) SMN1; SMN2POLBCXCR4CHRM5CHRM3
SCHEMBL4005712 0.78 SIGMAR1 (0.35) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL2508441 0.77 HRH3 (0.33) SMN1; SMN2MEN1KMT2ACHRM5ALDH1A1
SCHEMBL1861629 0.77 SMN1; SMN2 (0.40) CYP1A2CHRM2SMN1; SMN2CXCR4SIGMAR1
SCHEMBL1995114 0.77 HRH3 (0.33) SMN1; SMN2MEN1KMT2ACHRM5ALDH1A1
SCHEMBL775087 0.76 CXCR4 (0.44) CHRM2SMN1; SMN2POLBMEN1KMT2A
SCHEMBL4071773 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
CN-116355222-B Washable amino and polyether co-modified polysiloxane and preparation method thereof 山东东岳有机硅材料股份有限公司 2025-05-13 CN disclosed
CN-116355222-A Washable amino and polyether co-modified polysiloxane and preparation method thereof 山东东岳有机硅材料股份有限公司 2023-06-30 CN disclosed
US-9074032-B2 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2015-07-07 US disclosed
EP-2414411-B1 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2013-02-20 EP disclosed
US-8137590-B2 Particles comprising zwitterionic structural elements WACKER CHEMIE AG (DE) 2012-03-20 US disclosed
US-20120031843-A1 Membranes based on polyvinyl alcohol WACKER CHEMIE AG (DE) 2012-02-09 US disclosed
EP-2414411-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL Wacker Chemie AG (DE) 2012-02-08 EP disclosed
EP-1940940-B1 PARTICLES COMPRISING ZWITTERIONIC STRUCTURAL ELEMENTS CONSORTIUM ELEKTROCHEM IND (DE) 2011-04-20 EP disclosed
WO-2010112372-A2 MEMBRANES BASED ON POLYVINYL ALCOHOL WACKER CHEMIE AG (DE) 2010-10-07 WO disclosed
EP-1824904-B1 ALKOXYSILANE-TERMINATED PREPOLYMERS WACKER CHEMIE AG (DE) 2008-11-05 EP disclosed
EP-1714968-B1 Protected piperazino group-bearing organoxysilane compound and making method SHINETSU CHEMICAL CO (JP) 2008-07-16 EP disclosed
WO-2008015123-A1 PREPARATION OF ACID DERIVATIVE-FUNCTIONAL ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2008-02-07 WO disclosed
WO-2008015120-A1 λ5-Si - SILICATE-FUNCTIONAL PREPOLYMERS WACKER CHEMIE AG (DE) 2008-02-07 WO disclosed
EP-1824904-A1 ALKOXYSILANE-TERMINATED PREPOLYMERS Wacker Chemie AG (DE) 2007-08-29 EP disclosed
EP-1824865-A2 HIGHLY REACTIVE ALPHA-AMINOMETHYL-ALKOXYSILANES HAVING IMPROVED STABILITY Wacker Chemie AG (DE) 2007-08-29 EP disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed
WO-2006061091-A2 HIGHLY REACTIVE $G(A)-AMINOMETHYL-ALKOXYSILANES HAVING IMPROVED STABILITY WACKER CHEMIE AG (DE) 2006-06-15 WO disclosed
WO-2006061090-A1 ALKOXYSILANE-TERMINATED PREPOLYMERS WACKER CHEMIE AG (DE) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM CYP1A2 3915/4885CHRM2 4118/4885SLC6A4 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.