Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 8/20 | 0.34 |
| ▸ | CTSS | P25774 | 7/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615942 | 0.90 | CTSK (0.41) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18616629 | 0.89 | CTSL (0.37) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18615967 | 0.88 | MAPK14 (0.35) | CTSLMAPK14 | |
| SCHEMBL20341828 | 0.88 | CTSL (0.37) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18616541 | 0.86 | CTSK (0.42) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18615975 | 0.86 | CTSL (0.35) | CTSLCTSKCTSSCTSB | |
| SCHEMBL20341764 | 0.86 | CTSL (0.38) | CTSLCTSKCTSSCTSB | |
| SCHEMBL20341771 | 0.86 | CTSL (0.38) | CTSLCTSKCTSSCTSB | |
| SCHEMBL23810283 | 0.85 | CTSL (0.38) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18615857 | 0.85 | CTSK (0.41) | CTSLCTSKCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |