Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 11/20 | 0.34 |
| ▸ | CTSS | P25774 | 10/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615947 | 0.92 | LMNA (0.35) | CTSLCYP2D6CTSKCTSSCTSB | |
| SCHEMBL18616629 | 0.90 | CTSL (0.37) | CTSLCTSKCTSSCTSB | |
| SCHEMBL18617423 | 0.90 | NAMPT (0.35) | CTSLCYP2D6CTSKCTSSCTSB | |
| SCHEMBL20341792 | 0.89 | CTSL (0.36) | CTSLCYP2D6CTSKCTSSCTSB | |
| SCHEMBL18616018 | 0.89 | LMNA (0.37) | CTSLCYP2D6CTSKCTSSCTSB | |
| SCHEMBL18615942 | 0.87 | CTSK (0.41) | CTSLCTSKCTSSCTSB | |
| SCHEMBL23810230 | 0.87 | CTSL (0.34) | CTSLCYP2D6CTSKCTSSCTSB | |
| SCHEMBL18615946 | 0.87 | CACNA1H (0.40) | CTSLCYP2D6CTSKCTSSPOLB | |
| SCHEMBL20341794 | 0.86 | CTSL (0.34) | CTSLCTSKCTSSCTSBGAA | |
| SCHEMBL18616528 | 0.86 | CTSL (0.37) | CTSLCTSKCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342765-B1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-3342765-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017036357-A1 | CATHEPSIN K INHIBITOR AND APPLICATION THEREOF | 广东东阳光药业有限公司 | 2017-03-09 | — | — | WO | disclosed |