Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198614 | 0.95 | MAOA (0.53) | MAOAMAOBKDM1A | |
| SCHEMBL933856 | 0.93 | MAOA (0.51) | MAOAMAOBKDM1A | |
| SCHEMBL164340 | 0.93 | MAOA (0.51) | MAOAMAOBKDM1A | |
| SCHEMBL9539801 | 0.91 | MAOA (0.56) | MAOAMAOBKDM1A | |
| SCHEMBL1610007 | 0.91 | MAOA (0.56) | MAOAMAOBKDM1A | |
| SCHEMBL29168417 | 0.82 | ALDH1A1 (0.44) | MAOAMAOB | |
| SCHEMBL1794186 | 0.81 | MAOA (0.49) | MAOAMAOBKDM1A | |
| SCHEMBL818902 | 0.81 | KDM1A (0.51) | MAOAMAOBKDM1A | |
| SCHEMBL20015683 | 0.81 | KDM1A (0.51) | MAOAMAOBKDM1A | |
| Hydrochloric Acid SCHEMBL7469122 | 0.79 | KDM1A (0.50) | MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017037116-A1 | PYRIDINONE DICARBOXAMIDE FOR USE AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-09 | — | — | WO | disclosed |