Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.59 |
| ▸ | MERTK | Q12866 | 3/20 | 0.56 |
| ▸ | AXL | P30530 | 2/20 | 0.56 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.54 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.54 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615504 | 0.87 | BMPR1B (0.68) | PIK3C3MERTKAXLBMPR1BBMPR1A | |
| SCHEMBL18611892 | 0.83 | MERTK (0.55) | PIK3C3MERTKAXLPIK3CBMET | |
| SCHEMBL18617157 | 0.82 | FYN (0.66) | PIK3C3MERTKAXLBMPR1BBMPR1A | |
| SCHEMBL24319038 | 0.80 | KCNH2 (0.67) | PIK3C3MERTKAXLBMPR1BBMPR1A | |
| SCHEMBL18615511 | 0.78 | BMPR1B (0.62) | PIK3C3MERTKAXLBMPR1BBMPR1A | |
| SCHEMBL18616316 | 0.78 | MERTK (0.57) | PIK3C3MERTKAXLBMPR1BBMPR1A | |
| SCHEMBL13515284 | 0.76 | KCNH2 (0.56) | MERTKAXLKCNH2LRRK2JAK2 | |
| SCHEMBL18616286 | 0.76 | MERTK (0.55) | PIK3C3MERTKAXLBMPR1BBMPR1A | |
| SCHEMBL18615786 | 0.75 | AXL (0.57) | MERTKAXLBMPR1BBMPR1AACVRL1 | |
| SCHEMBL24838842 | 0.75 | MERTK (0.74) | MERTKAXLBMPR1BBMPR1AACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | disclosed |
| EP-3344613-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2020-03-04 | — | — | EP | disclosed |
| WO-2017039331-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2017-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | PIK3C3 322/4885MERTK 1/4885AXL 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.