Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | TACR1 | P25103 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20671885 | 0.84 | DRD2 (0.43) | HTR2CHTR2AHTR2BSSTR1SSTR4 | |
| SCHEMBL30228462 | 0.83 | P2RY14 (0.41) | P2RY14HTR2CTACR1SSTR1SSTR4 | |
| SCHEMBL18617804 | 0.83 | SLC5A1 (0.37) | HTR2CSSTR1SSTR4SLC6A2SLC6A4 | |
| SCHEMBL23873173 | 0.80 | HTR2C (0.60) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| SCHEMBL26115367 | 0.80 | HTR2C (0.60) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| SCHEMBL26515976 | 0.80 | HTR2C (0.60) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| SCHEMBL30228519 | 0.79 | DRD2 (0.47) | P2RY14HTR2CSSTR1SSTR4 | |
| SCHEMBL13646151 | 0.78 | SSTR1 (0.40) | P2RY14TACR1SSTR1SSTR4 | |
| SCHEMBL13646153 | 0.78 | SSTR1 (0.40) | P2RY14TACR1SSTR1SSTR4 | |
| SCHEMBL13646152 | 0.78 | SSTR1 (0.40) | P2RY14TACR1SSTR1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126840-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |