Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18581470 | 0.85 | RXRA (0.42) | RXRAGRIN1GRIN2BMAPTL3MBTL1 | |
| SCHEMBL18617892 | 0.85 | RXRA (0.42) | RXRAGRIN1GRIN2BMAPTTP53 | |
| SCHEMBL18581168 | 0.80 | PTGS2 (0.42) | RXRAGRIN1GRIN2BL3MBTL1POLB | |
| SCHEMBL14617482 | 0.80 | POLB (0.46) | RXRAGRIN1GRIN2BMAPTL3MBTL1 | |
| SCHEMBL27603083 | 0.78 | NOTUM (0.42) | TP53L3MBTL1TSHRCYP1A2CYP2C9 | |
| SCHEMBL18579377 | 0.78 | TRPA1 (0.38) | RXRAGRIN1GRIN2BMAPTTP53 | |
| SCHEMBL18586496 | 0.78 | RXRA (0.43) | RXRAGRIN1GRIN2BMAPTL3MBTL1 | |
| SCHEMBL18617196 | 0.78 | RXRA (0.43) | RXRAGRIN1GRIN2BMAPTL3MBTL1 | |
| SCHEMBL14577291 | 0.77 | RXRA (0.42) | RXRAGRIN1GRIN2BMAPTTP53 | |
| SCHEMBL18581113 | 0.77 | RXRA (0.42) | RXRAGRIN1GRIN2BMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040194-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2017-03-09 | — | — | WO | disclosed |