Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060289 | 0.77 | SIGMAR1 (0.58) | SIGMAR1NOS1KDM4ESMN1; SMN2 | |
| SCHEMBL20111343 | 0.77 | — | — | |
| SCHEMBL11301865 | 0.75 | SIGMAR1 (0.61) | SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL28300346 | 0.75 | SIGMAR1 (0.61) | SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL17573327 | 0.74 | LTA4H (0.37) | TSHRKDM4ESMN1; SMN2 | |
| Iodide SCHEMBL27688321 | 0.74 | SIGMAR1 (0.59) | SIGMAR1KDM4ESMN1; SMN2 | |
| SCHEMBL18620013 | 0.74 | — | — | |
| SCHEMBL26085538 | 0.72 | SIGMAR1 (0.38) | SIGMAR1NOS1KDM4E | |
| SCHEMBL18559452 | 0.71 | HTT (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL14607759 | 0.69 | ATM (0.44) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040271-A1 | MODIFIED ANTISENSE OLIGOMERS FOR EXON INCLUSION IN SPINAL MUSCULAR ATROPHY | SAREPTA THERAPEUTICS, INC. (US) | 2017-03-09 | — | — | WO | disclosed |