Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 7/20 | 0.68 |
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.46 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22811419 | 1.00 | PREP (0.68) | PREPDPP4NPC1GAARAB9A | |
| SCHEMBL26563985 | 0.86 | DPP4 (0.53) | PREPDPP4NPC1GAARAB9A | |
| SCHEMBL22811118 | 0.84 | ALDH1A1 (0.55) | PREPDPP4FAPACEDPP8 | |
| SCHEMBL22811227 | 0.81 | DPP4 (0.59) | PREPDPP4FAPACEDPP8 | |
| SCHEMBL22811334 | 0.80 | PREP (0.66) | PREPDPP4GAARAB9AFAP | |
| SCHEMBL22209472 | 0.79 | DPP4 (0.62) | PREPDPP4NPC1GAARAB9A | |
| SCHEMBL18620672 | 0.79 | ELANE (0.53) | PREP | |
| SCHEMBL22209446 | 0.79 | ELANE (0.53) | PREP | |
| SCHEMBL22209388 | 0.78 | PREP (0.58) | PREPDPP4NPC1GAARAB9A | |
| SCHEMBL13739448 | 0.77 | EPHX2 (0.68) | GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |