Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 7/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18619638 | 0.93 | MALT1 (0.57) | MALT1CTSKCTSLCTSSOPRM1 | |
| SCHEMBL18619694 | 0.86 | MALT1 (0.65) | MALT1OPRM1OPRK1REN | |
| SCHEMBL18620806 | 0.86 | MALT1 (0.65) | MALT1OPRM1OPRK1REN | |
| SCHEMBL18619636 | 0.85 | MALT1 (0.55) | MALT1OPRM1OPRK1RENDPP4 | |
| SCHEMBL22209464 | 0.85 | MALT1 (0.57) | MALT1OPRM1OPRK1RENDPP4 | |
| SCHEMBL18619693 | 0.84 | MALT1 (0.56) | MALT1OPRM1OPRK1RENDPP4 | |
| SCHEMBL18619697 | 0.84 | MALT1 (0.56) | MALT1OPRM1OPRK1RENDPP4 | |
| SCHEMBL18619642 | 0.84 | MALT1 (0.55) | MALT1OPRM1OPRK1RENDPP4 | |
| SCHEMBL22811073 | 0.84 | MALT1 (0.64) | MALT1 | |
| SCHEMBL22209365 | 0.84 | MALT1 (0.64) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |