Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17701589 | 0.84 | ALOX12 (0.34) | ALOX12PIK3CDKDM4EPOLBLMNA | |
| SCHEMBL22757181 | 0.84 | ALOX12 (0.34) | ALOX12PIK3CDKDM4EPOLBLMNA | |
| SCHEMBL22970122 | 0.81 | ALOX12 (0.35) | ALOX12KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL20420073 | 0.81 | ALOX12 (0.33) | ALOX12PIK3CDKDM4EPOLBLMNA | |
| SCHEMBL18532376 | 0.79 | ALOX12 (0.34) | ALOX12KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL21786204 | 0.78 | ALOX12 (0.36) | ALOX12KDM4EPOLBLMNASMN1; SMN2 | |
| SCHEMBL24114378 | 0.78 | ALOX12 (0.33) | ALOX12KDM4EPOLBLMNATSHR | |
| SCHEMBL21118020 | 0.78 | ALOX12 (0.33) | ALOX12KDM4EPOLBLMNAMEN1 | |
| SCHEMBL20725208 | 0.75 | ALOX12 (0.32) | ALOX12KDM4EPOLBKMT2A | |
| SCHEMBL3859731 | 0.75 | KDM4E (0.35) | ALOX12KDM4EPOLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020043747-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Belyntic GmbH (DE) | 2020-03-05 | — | — | WO | disclosed |
| US-9795685-B2 | Haptens of aripiprazole | JANSSEN PHARMACEUTICA NV (BE) | 2017-10-24 | — | — | US | disclosed |
| US-20170072061-A1 | HAPTENS OF ARIPIPRAZOLE | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072061-A1 | HAPTENS OF ARIPIPRAZOLE | HRH2, HRH4, CYP2D6 | ALOX12 1962/4885PIK3CD 2479/4885KDM4E 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.