SCHEMBL22970122

SCHEMBL22970122

CCC(C)CON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ALOX12 P18054 1/20 0.35
▸ IGF1R P08069 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ LMNA P02545 2/20 0.32
▸ MAPT P10636 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24114378 0.85 ALOX12 (0.33) ALOX12KDM4EPOLBLMNA
SCHEMBL18532376 0.82 ALOX12 (0.34) ALOX12KDM4EPOLBLMNASMN1; SMN2
SCHEMBL22757181 0.82 ALOX12 (0.34) ALOX12KDM4EPOLBLMNASMN1; SMN2
SCHEMBL21786204 0.82 ALOX12 (0.36) ALOX12KDM4EPOLBLMNASMN1; SMN2
SCHEMBL18624174 0.81 ALOX12 (0.38) ALOX12KDM4EPOLBLMNASMN1; SMN2
SCHEMBL14982619 0.77 MAPT (0.35) MAPTSMN1; SMN2
SCHEMBL20725208 0.74 ALOX12 (0.32) ALOX12KDM4EPOLB
SCHEMBL1710103 0.73 ALOX12 (0.41) ALOX12KDM4EPOLBLMNAMAPT
SCHEMBL21118020 0.73 ALOX12 (0.33) ALOX12KDM4EPOLBLMNA
SCHEMBL12992690 0.73 ADORA3 (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219446-A2 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Gyros Protein Technologies AB (SE) 2023-08-02 — — EP disclosed
WO-2021023892-A1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES Belyntic GmbH (DE) 2021-02-11 — — WO disclosed
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