Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757181 | 0.81 | ALOX12 (0.34) | ALOX12PIK3CDKDM4EPOLBLMNA | |
| SCHEMBL18624174 | 0.81 | ALOX12 (0.38) | ALOX12PIK3CDKDM4EPOLBLMNA | |
| SCHEMBL19172387 | 0.78 | MEN1 (0.37) | LMNA | |
| SCHEMBL22970122 | 0.72 | ALOX12 (0.35) | ALOX12KDM4EPOLBLMNA | |
| SCHEMBL17701589 | 0.70 | ALOX12 (0.34) | ALOX12PIK3CDKDM4EPOLBLMNA | |
| SCHEMBL18532376 | 0.70 | ALOX12 (0.34) | ALOX12KDM4EPOLBLMNA | |
| SCHEMBL21786204 | 0.69 | ALOX12 (0.36) | ALOX12KDM4EPOLBLMNA | |
| SCHEMBL24114378 | 0.69 | ALOX12 (0.33) | ALOX12KDM4EPOLBLMNA | |
| SCHEMBL21118020 | 0.69 | ALOX12 (0.33) | ALOX12KDM4EPOLBLMNA | |
| SCHEMBL3859731 | 0.67 | KDM4E (0.35) | ALOX12KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405577-B1 | COMPOSITIONS AND METHODS FOR INHIBITING FACTOR D | 396419 B C LTD (CA) | 2022-12-14 | — | — | EP | disclosed |
| WO-2018136831-A1 | PSEUDOKNOT COMPOSITIONS AND METHODS FOR INHIBITING FACTOR D | VITRISA THERAPEUTICS, INC. (US) | 2018-07-26 | — | — | WO | disclosed |