Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18624654 | 0.71 | HRH3 (0.35) | CHRNB4CHRNA3SLC6A2SLC6A3CARM1 | |
| SCHEMBL26348163 | 0.67 | SLC6A2 (0.44) | CHRNB4CHRNA3SLC6A2SLC6A3CARM1 | |
| SCHEMBL16004566 | 0.67 | USP30 (0.45) | CHRNA7 | |
| SCHEMBL11170273 | 0.61 | CHRNB4 (0.46) | CHRNB4CHRNA3SLC6A2SLC6A3CARM1 | |
| SCHEMBL3436987 | 0.60 | SMN1; SMN2 (0.71) | SLC6A2SLC6A3CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL16707767 | 0.60 | SLC6A2 (0.53) | SLC6A2SLC6A3CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL24804361 | 0.59 | SLC6A2 (0.56) | CHRNB4CHRNA3SLC6A2SLC6A3CARM1 | |
| SCHEMBL9683676 | 0.59 | SLC6A2 (0.56) | SLC6A2SLC6A3CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL714763 | 0.59 | SMN1; SMN2 (0.59) | SLC6A2SLC6A3CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL10262302 | 0.59 | SMN1; SMN2 (0.59) | SLC6A2SLC6A3CARM1PRMT6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170072390-A1 | SYNTHESIS OF ACYCLIC AND CYCLIC AMINES USING IRON-CATALYZED NITRENE GROUP TRANSFER | FTH1, FLI1, FECH | CHRNB4 3935/4885CHRNA3 3130/4885SLC6A2 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.