SCHEMBL26348163

SCHEMBL26348163

CN1CC=CCN(C)C1Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.44
SLC6A3 Q01959 4/20 0.44
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
CHRNB4 P30926 3/20 0.38
CHRNA3 P32297 3/20 0.38
HRH1 P35367 1/20 0.37
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
CHRNA7 P36544 1/20 0.36
SLC6A4 P31645 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA4 P22748 1/20 0.34
CTSV O60911 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
CTSC P53634 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18624652 0.67 CHRNB4 (0.38) SLC6A2SLC6A3CARM1PRMT6CHRNB4
SCHEMBL9683676 0.67 SLC6A2 (0.56) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL24804361 0.67 SLC6A2 (0.56) SLC6A2SLC6A3CARM1PRMT6CHRNB4
SCHEMBL11170273 0.65 CHRNB4 (0.46) SLC6A2SLC6A3CARM1PRMT6CHRNB4
SCHEMBL12384356 0.64 SLC6A2 (0.53) SLC6A2SLC6A3CARM1PRMT6CHRNB4
SCHEMBL4159715 0.64 CHRNB2 (0.65) CHRNB4CHRNA3CHRNB2CHRNA4CHRNA7
SCHEMBL28956135 0.64 SLC6A2 (0.49) SLC6A2SLC6A3CARM1PRMT6CHRNB4
SCHEMBL3436987 0.64 SMN1; SMN2 (0.71) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL11048663 0.64 HRH3 (0.45) SLC6A2SLC6A3CARM1PRMT6CHRNB4
SCHEMBL16707767 0.64 SLC6A2 (0.53) SLC6A2SLC6A3CARM1PRMT6HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303776-A1 FULLY AND PARTIALLY BACKBONE-DEGRADABLE POLYMERS VIA LOW TEMPERATURE RING-OPENING METATHESIS POLYMERIZATION (ROMP) NORTHWESTERN UNIVERSITY (US) 2023-09-28 US disclosed