SCHEMBL186253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL186808	0.94	GCGR (0.43)	GCGRALDH1A1KMT2ATP53MITF
	SCHEMBL187180	0.83	GCGR (0.38)	GCGRALDH1A1KMT2ATP53MITF
	SCHEMBL185969	0.78	NPC1 (0.53)	GCGRALDH1A1TP53LMNASMN1; SMN2
	SCHEMBL23758527	0.74	GCGR (0.47)	GCGRALDH1A1KMT2ATP53MITF
	SCHEMBL10065678	0.72	GCGR (0.48)	GCGRALDH1A1KMT2ATP53MITF
	SCHEMBL10065679	0.72	GCGR (0.40)	GCGRALDH1A1KMT2ATP53MITF
	SCHEMBL28553754	0.71	GCGR (0.64)	GCGR
	SCHEMBL31168900	0.69	KIF11 (0.42)	ALDH1A1KMT2ATP53LMNASMN1; SMN2
	SCHEMBL13183793	0.69	GCGR (0.42)	GCGRALDH1A1KMT2ATP53MITF
	SCHEMBL186558	0.69	MEN1 (0.38)	GCGRALDH1A1KMT2ATNKSLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.