Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329075 | 0.83 | RAB9A (0.51) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL14770901 | 0.80 | MPO (0.49) | NPC1RAB9AKDM4EATMMAPT | |
| SCHEMBL28442582 | 0.79 | ALDH1A1 (0.45) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL186253 | 0.78 | GCGR (0.47) | NPC1RAB9AKDM4EMAPTLMNA | |
| SCHEMBL186808 | 0.73 | GCGR (0.43) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL4793206 | 0.71 | GCGR (0.65) | GCGRMAPK14 | |
| SCHEMBL18190288 | 0.70 | CSF1R (0.40) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL16976741 | 0.69 | PDE4A (0.55) | NPC1RAB9AKDM4EATMMAPT | |
| SCHEMBL15572536 | 0.69 | NPC1 (1.00) | NPC1RAB9AKDM4EHPGDHSD17B10 | |
| SCHEMBL27642153 | 0.69 | NPC1 (0.68) | NPC1RAB9AKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778510-B2 | Pyrromethene-boron complex compounds and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2014-07-15 | — | — | US | disclosed |
| EP-2402351-B1 | PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO (JP) | 2013-10-09 | — | — | EP | disclosed |
| US-20120037890-A1 | PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | MITSUI CHEMICALS, INC. | 2012-02-16 | — | — | US | disclosed |
| EP-2402351-A1 | PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |
| EP-0786925-B1 | White light-emitting electroluminescent devices | EASTMAN KODAK CO (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-0596098-B1 | FLUORESCENT MICROPARTICLES WITH CONTROLLABLE ENHANCED STOKES SHIFT | MOLECULAR PROBES INC (US) | 1998-06-17 | — | — | EP | disclosed |
| EP-0612336-B1 | LONG WAVELENGTH CHEMICALLY REACTIVE DIPYRROMETHENEBORON DIFLUORIDE DYES AND CONJUGATES | MOLECULAR PROBES INC (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5683823-A | 4,4-DIFLUROR-4-BORA-3A,4A-DIAZA-S-INDACENE GUEST COMPONENT | EASTMAN KODAK COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| EP-0786925-A2 | White light-emitting electroluminescent devices | EASTMAN KODAK COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5573909-A | DETECTING MULTIPLE DIFFERENT TARGET SPECIFIC BINDING PAIR MEMBER IN SAMPLE BY USING PROBES COMPRISING POLYMERIC MICROPARTICLE CONTAINING DISPERSED SERIES OF FLUORESCENT DYES, AND COMPLEMENTARY SPECIFIC BINDING PAIR MEMBER | MOLECULAR PROBES, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5451663-A | Fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| US-5338854-A | Detectors for study of natural or synthetic lipid membranes | MOLECULAR PROBES, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| US-5326692-A | Polyazaindacene dyes | MOLECULAR PROBES, INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0596098-A1 | FLUORESCENT MICROPARTICLES WITH CONTROLLABLE ENHANCED STOKES SHIFT | MOLECULAR PROBES, INC. (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5274113-A | Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates | MOLECULAR PROBES, INC. (US) | 1993-12-28 | — | — | US | disclosed |
| WO-1993023492-A1 | FLUORESCENT MICROPARTICLES WITH CONTROLLABLE ENHANCED STOKES SHIFT | MOLECULAR PROBES, INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5248782-A | Fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1993-09-28 | — | — | US | disclosed |
| US-5187288-A | Electrically neutral, photostable, narrow absorption and emission spectra | MOLECULAR PROBES, INC. (US) | 1993-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120037890-A1 | PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | LEF1, ZRANB2, AFF1 | NPC1 1898/4885RAB9A 1128/4885KDM4E 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.