Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263157 | 0.87 | HDAC8 (0.51) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL18625822 | 0.82 | CYP19A1 (0.55) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL16264702 | 0.82 | HDAC8 (0.54) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL18625972 | 0.80 | HDAC8 (0.58) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL19723300 | 0.78 | HDAC8 (0.53) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL19535082 | 0.77 | HDAC8 (0.62) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL18625958 | 0.75 | HDAC8 (0.51) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL18625975 | 0.75 | LGALS3 (0.36) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL18625974 | 0.74 | KDR (0.51) | HDAC8HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22868031 | 0.73 | HDAC8 (0.41) | HDAC8HDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593140-B2 | Antibacterial tylosin derivatives and methods for their preparation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-03-14 | — | — | US | disclosed |