Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813660 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL186269 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| Cyanide SCHEMBL28871133 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3228382 | 0.77 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL19062287 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL2074858 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL186554 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5546112 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1KDM4EL3MBTL1KMT2AMAPT | |
| SCHEMBL16957365 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL286715 | 0.73 | CYP1A2 (0.50) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992012-B2 | Diaminotriazine compounds | BASF SE (DE) | 2024-05-28 | — | — | US | disclosed |
| US-20210186021-A1 | DIAMINOTRIAZINE COMPOUNDS | BASF SE (DE) | 2021-06-24 | — | — | US | disclosed |
| US-10959432-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-30 | — | — | US | disclosed |
| US-10757941-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-01 | — | — | US | disclosed |
| US-20200267986-A1 | Microbiocidal Oxadiazole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-10687533-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-23 | — | — | US | disclosed |
| EP-3439477-B1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-06 | — | — | EP | disclosed |
| US-20190274304-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | US | disclosed |
| US-20190090486-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| WO-2015048547-A2 | METHODS FOR USING AND BIOMARKERS FOR AMPK-ACTIVATING COMPOUNDS | RIGEL PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| EP-2598483-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | Rigel Pharmaceuticals, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012016217-A1 | AMPK-ACTIVATING HETEROCYCLIC COMPOUNDS AND METHODS FOR USING THE SAME | RIGEL PHARMACEUTICALS, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10959432-B2 | Microbiocidal oxadiazole derivatives | PRF1, NOX1, ARG1 | ALDH1A1 489/4885KDM4E 2561/4885HPGD 1015/4885 |
| US-20210186021-A1 | DIAMINOTRIAZINE COMPOUNDS | DDT, DAZAP1, DDC | ALDH1A1 991/4885KDM4E 1586/4885HPGD 1677/4885 |
| US-11992012-B2 | Diaminotriazine compounds | DDT, DAZAP1, DDC | ALDH1A1 991/4885KDM4E 1586/4885HPGD 1677/4885 |
| US-10687533-B2 | Microbiocidal oxadiazole derivatives | PRF1, NOX1, ARG1 | ALDH1A1 489/4885KDM4E 2561/4885HPGD 1015/4885 |
| US-10757941-B2 | Microbiocidal oxadiazole derivatives | PRF1, NOX1, ARG1 | ALDH1A1 476/4885KDM4E 2601/4885HPGD 1017/4885 |
| US-20200267986-A1 | Microbiocidal Oxadiazole Derivatives | PRF1, NOX1, ARG1 | ALDH1A1 489/4885KDM4E 2561/4885HPGD 1015/4885 |
| US-20190090486-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | ALDH1A1 489/4885KDM4E 2561/4885HPGD 1015/4885 |
| US-20190274304-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | ALDH1A1 476/4885KDM4E 2601/4885HPGD 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.