Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21369562 | 0.80 | RAB9A (0.47) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL18627205 | 0.73 | RAB9A (0.44) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL17234471 | 0.73 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL18528347 | 0.73 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL1144419 | 0.72 | RAB9A (0.49) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL1144420 | 0.72 | RAB9A (0.49) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL24870922 | 0.69 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL12726207 | 0.69 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL16418407 | 0.69 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2AGAA | |
| SCHEMBL25830149 | 0.69 | RAB9A (0.56) | RAB9ANPC1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593103-B2 | Pyridyl hydrazones for the treatment of tuberculosis and related diseases | TECNIMEDE SOCIEDADE TECNICO-MEDICINAL S.A. (PT) | 2017-03-14 | — | — | US | disclosed |